3.2. Sample size determination

There are many online sample size calculators available on the internet that differ in the parameters required to calculate sample size for experiments. Some are based on the effect size or minimal detectable difference (see section 3.1.3.); for others input on the estimated mean (µ) and standard deviation (ä) for the different treatment groups is required. Fundamentally, the design of the experiment, the required power, the allowed α and the expected effect size dictate the required sample size. The following two sections (3.2.1. and 3.2.2.) suggest strategies for determining sample size.

3.2.3. Sample size and individual infection rates